index - CRCL-Petites molécules pour cibles biologiques

Alexandre Bancet, Rita Frem, Florian Jeanneret, Angélique Mularoni, Pauline Bazelle, et al.. Cancer selective cell death induction by a bivalent CK2 inhibitor targeting the ATP site and the allosteric αD pocket. iScience, 2024, 27 (2), pp.108903. ⟨10.1016/j.isci.2024.108903⟩. ⟨hal-04424788⟩
Jean Guillon, Marc Le Borgne, Vittoria Milano, Aurore Guédin-Beaurepaire, Stéphane Moreau, et al.. New 2,4-bis[(substituted-aminomethyl)phenyl]phenylquinazoline and 2,4-bis[(substituted-aminomethyl)phenyl]phenylquinoline derivatives: synthesis and biological evaluation as novel anticancer agents by targeting G-quadruplex. Pharmaceuticals, 2024, 17 (1), pp.30. ⟨10.3390/ph17010030⟩. ⟨hal-04390485⟩
Jean-Louis Banères, Thomas Botzanowski, Jean A Boutin, Barbara Calamini, Jérôme Castel, et al.. Biophysical Dissection of Isolated GPCRs: The Adenosine A2A Receptor under the Bistouries. Receptors and Channels, 2023, 2 (1), pp.47-92. ⟨10.3390/receptors2010004⟩. ⟨hal-04003751⟩
Hubert Gorny, Angélique Mularoni, Jean-Guy Delcros, Céline Freton, Jordane Preto, et al.. Combining nano-differential scanning fluorimetry and microscale thermophoresis to investigate VDAC1 interaction with small molecules. Journal of Enzyme Inhibition and Medicinal Chemistry, 2023, 38 (1), pp.2121821. ⟨10.1080/14756366.2022.2121821⟩. ⟨hal-04235221⟩
Julie GIL, Isabelle Krimm, Vincent Dugas, Claire Demesmay. Preparation of miniaturized hydrophilic affinity monoliths: Towards a reduction of non-specific interactions and an increased target protein density. Journal of Chromatography A, 2023, 1687, pp.463670. ⟨10.1016/j.chroma.2022.463670⟩. ⟨hal-03888930⟩
Dylan Grenier, Solène Audebert, Jordane Preto, Jean-François Guichou, Isabelle Krimm. Linkers in fragment-based drug design: an overview of the literature. Expert Opinion on Drug Discovery, 2023, 18 (9), pp.987-1009. ⟨10.1080/17460441.2023.2234285⟩. ⟨hal-04235200⟩

Derniers manuscrits de l'équipe

Chiffres clés